hCXCR5(BALB/c)

Nomenclature

BALB/cAnSmoc-Cxcr5tm1(hCXCR5)Smoc

Cat. NO.

NM-HU-234732

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cxcr5

Synonyms

Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

Chromosome

9

NCBI ID

12145

MGI ID

103567

Ensembl ID

ENSMUSG00000047880

Pubmed

Cxcr5

Human Ortholog

CXCR5

Model Description

The endogenous mouse Cxcr5 gene was replaced by human CXCR5 gene.

Validation Data

image.png

Fig.1 Expression analysis of mCXCR5 and hCXCR5 in spleen and blood in heterozygous CXCR5 humanized mice. 

Leukocytes were collected from WT (male, 6 weeks old) and HE hCXCR5 mice (male, 6 weeks old), and analyzed by flow cytometry with anti-mCXCR5 and anti-hCXCR5. mCXCR5 were detectable in WT mice and HE hCXCR5 mice. hCXCR5 were exclusively detectable in HE hCXCR5 mice but not in WT mice.

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