hEBI3

Nomenclature

C57BL/6Smoc-Ebi3tm1(hEBI3)Smoc

Cat. NO.

NM-HU-234509

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ebi3

Synonyms

EBI-3; IL-27

NCBI ID

50498

MGI ID

1354171

Ensembl ID

ENSMUSG00000003206

Pubmed

Ebi3

Human Ortholog

EBI3

Model Description

The endogenous mouse Ebi3 gene was replaced by human EBI3 gene.

Validation Data

image.png

Fig.1 Detection of EBI3 expression in spleen by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1(mEbi3); 

Homozygous: only one band at 117 bp with primers F2/R2(hEBI3). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hEBI3 expression in serum by ELISA. 

Abbr. HO, homozygous; WT, wild type. 

Note. hEBI3 and C57BL/6 mice were i.p. injected with LPS. The human EBI3 ELISA kit cross- reacted with mEBI3 and humanized EBI3.

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