hGPC3

Nomenclature

C57BL/6Smoc-Gpc3tm1(hGPC3)Smoc

Cat. NO.

NM-HU-234374

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gpc3

Synonyms

OCI-5

NCBI ID

14734

MGI ID

104903

Ensembl ID

ENSMUSG00000055653

Pubmed

Gpc3

Human Ortholog

GPC3

Model Description

The endogenous mouse Gpc3 gene was replaced by human GPC3 gene.

Validation Data

image.png

Fig.1 Detection of GPC3 expression in kidney by RT-PCR. 

Wild type: only one band at 547 bp with primers F1/R1(mGpc3);

Homozygous: only one band at 219 bp with primers F2/R2(hGPC3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GPC3 expression in hGPC3 mice by WB. 

Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, Hepa1-6 cells.

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