hKLRG1(3)

Nomenclature

C57BL/6Smoc-Klrg1tm3(hKLRG1)Smoc

Cat. NO.

NM-HU-234277

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Klrg1

Synonyms

MAFA; 2F1-Ag; MAFA-L

NCBI ID

50928

MGI ID

1355294

Ensembl ID

ENSMUSG00000030114

Pubmed

Klrg1

Human Ortholog

KLRG1

Model Description

The endogenous mouse Klrg1 gene was replaced by human KLRG1 gene.

Validation Data

image.png

Fig.1 Detection of KLRG1 expression in spleen by RT-PCR. 

Wild type: only one band at 194 bp with primers F1/R1(mKlrg1);

Homozygous: only one band at 185 bp with primers F2/R2(hKLRG1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of mKLRG1 expression on NK cells and T cells in peripheral blood. (male, 9 weeks old)

image.png

Fig.3 Detection of hKLRG1 expression on NK cells and T cells in peripheral blood. (male, 9 weeks old)

image.png

Fig.4 Detection of mKLRG1 expression on NK cells and T cells in Spleen. (male, 9 weeks old)

image.png

Fig.5 Detection of hKLRG1 expression on NK cells and T cells in Spleen. (male, 9 weeks old)

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more