hIL15

Nomenclature

C57BL/6Smoc-Il15tm1(hIL15)Smoc

Cat. NO.

NM-HU-233147

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il15

Model Description

The endogenous mouse Il15 gene was replaced by human IL15 gene.

Validation Data

image.png

Fig.1 Detection of IL15 expression in the duodenum by RT-PCR. 

Wild type: only one band at 268 bp with primers F1/R1(mIl15);

Homozygous: only one band at 305 bp with primers F2/R2(hIL15).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human IL15 expression in serum by ELISA (male, 7-8wks, n=2). 

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.

Note. The hIL15 and C57BL/6 mice were i.p. injected with LPS for 2h.


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