hCD7(V2)

Nomenclature

C57BL/6Smoc-Cd7tm2(hCD7)Smoc

Cat. NO.

NM-HU-232423

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cd7

Model Description

The endogenous mouse Cd7 gene was replaced by human CD7 gene.

Validation Data

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Fig.1 Detection of CD7 expression in duodenum and small intestine by RT-PCR. 

Wild type: only one band at 107 bp with primers F1/R1 (mCd7);

Homozygous: only one band at 163 bp with primers F2/R2 (hCD7).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of m/h CD7 expression on T cells in Blood (A), spleen (B) and thymus (C) in hCD7(2) KI mice.

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Fig.3 Detection of hCD7 expression on T cells in Blood (A), spleen (B) and thymus (C) in hCD7(2) KI mice.

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Fig.4 Detection of m/h CD7 expression on NKs in Blood (A) and spleen (B) in hCD7(2) KI mice.

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Fig.5 Analysis of leukocytes cell subpopulation in Spleen (A) and thymus (B) in WT and HO hCD7(2) mice.


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