hNTRK1

Nomenclature

C57BL/6Smoc-Ntrk1tm(hNTRK1)Smoc

Cat. NO.

NM-HU-230058

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ntrk1

Synonyms

Tkr; trk; TrkA; C80751

Chromosome

3

NCBI ID

18211

MGI ID

97383

Ensembl ID

ENSMUSG00000028072

Pubmed

Ntrk1

Human Ortholog

NTRK1

Model Description

The endogenous mouse Ntrk1 gene was replaced by human NTRK1 gene.

Validation Data

image.png

Fig.1 Detection of NTRK1 expression in adrenal by RT-PCR. 

Wild type: only one band at 146 bp with primers F1/R1(mNtrk1);

Homozygous:  only one band at 148 bp with primers F2/R2(hNTRK1). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human NTRK1 expression in hNTRK1 knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, MCF-7 cells.

Note. The anti-human NTRK1 antibody cross-reacted with mouse NTRK1 and humanized NTRK1.


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