hTFR1(3)

Nomenclature

C57BL/6Smoc-Tfrctm3(hTFRC)Smoc

Cat. NO.

NM-HU-230029

Strain State

Repository Live

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Gene Summary

Gene Symbol
Tfrc

Synonyms

TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; 2610028K12Rik; E430033M20Rik

Chromosome

16

NCBI ID

22042

MGI ID

98822

Ensembl ID

ENSMUSG00000022797

Pubmed

Tfrc

Human Ortholog

TFRC

Model Description

The endogenous mouse Tfrc gene was replaced by human TFRC gene.

Validation Data

image.png

Fig.1 Detection of TFR1(3) expression in liver and brain by RT-PCR. 

Wild type: only one band at 243 bp with primers F1/R1(mTfrc); 

Homozygous: only one band at 279 bp with primers F2/R2(hTFRC). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of CD71 expression in Blood in WT C57BL/6 and hTFR(3) mice.

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Fig.3 Detection of CD71 expression in Spleen in WT C57BL/6 and hTFR(3) mice.

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