hLTF(2)

Nomenclature

C57BL/6Smoc-Csn2tm(hLTF)Smoc

Cat. NO.

NM-HU-230019

Strain State

Repository Live

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Gene Summary

Gene Symbol
Csn2

Model Description

The endogenous mouse Csn2 gene was replaced by human LTF gene.

Validation Data

Fig.1 Detection of LTF expression in thymus of WT C57BL/6 (8-10 weeks old, male) and HO hLTF(2) (7 weeks old, male) mice by RT-PCR.

Wild type: only one band at 364 bp with primers F1/R1(mCsn2);

Homozygous: only one band at 383 bp with primers F2/R2(hLTF).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human LTF expression in the milk from hLTF mice by ELISA (13 weeks old, female) . 

Abbr.  HO, homozygous.


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