hCLEC6A

Nomenclature

C57BL/6Smoc-Clec4ntm(hCLEC6A)Smoc

Cat. NO.

NM-HU-220516

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Clec4n

Synonyms

Nkcl; Clec6a; Clecsf10

Chromosome

6

NCBI ID

56620

MGI ID

1861231

Ensembl ID

ENSMUSG00000023349

Pubmed

Clec4n

Human Ortholog

CLEC6A

Model Description

The endogenous mouse Clec4n gene was replaced by human CLEC6A gene.

Validation Data

image.png

Fig.1 Detection of CLEC6A expression in spleen and thymus by RT-PCR. 

Wild type: only one band at 189 bp with primers F1/R1(mClec4n);

Homozygous: only one band at 194 bp with primers F2/R2(hCLEC6A).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human and mouse CLEC6A expression on MHC-II+ BMDCs by FACS. 

The BMDCs were activated by GM-CSF and mIL-4 before detection.  (male, HO: 10wks, WT: 8-10wks)

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