hLRRC32
Nomenclature
C57BL/6Smoc-Lrrc32tm(hLRRC32)Smoc
Cat. NO.
NM-HU-220498
Strain State
Repository Live
Gene Summary
Gene Symbol
Lrrc32
Model Description
Validation Data
Fig.1 Detection of LRRC32 expression on platelets and Treg cells from WT C57BL/6 and HO hLRRC32 mice in the resting state. (male, 21 weeks old)
The results show that in the resting state, platelets from homozygous hLRRC32 mice highly express hLRRC32, and Tregs highly express hLRRC32; platelets from WT mice highly express mLRRC32, while Tregs barely express mLRRC32.
Fig.2 Detection of LRRC32 expression on Treg cells from WT C57BL/6 and HO hLRRC32 mice after stimulation. (male, 21 weeks old)
The results show that after stimulating sorted CD4+ T cells, Tregs from homozygous hLRRC32 mice highly express hLRRC32, while Tregs from WT mice highly express mLRRC32.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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