hIL22

Nomenclature

C57BL/6Smoc-Il22em(hIL22)Smoc

Cat. NO.

NM-HU-220419

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il22

Model Description

The endogenous mouse Il22 gene was replaced by human IL22 gene. This item was made available for sale on February 25, 2026.

Validation Data

image.png

Fig.1 Detection of IL22 expression in cerebellum by RT-PCR. 

Wild type: only one band at 486 bp with primers F1/R1(mIl22);

Homozygous: only one band at 356 bp with primers F2/R2(hIL22).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig. 2 Detection of human IL22 expression(A) and mouse IL22(B)  in serum by ELISA. (n=3 for both groups )

Abbr.  HO, homozygous; WT, wild type; N.D. not detected.

Note. The hIL22 and C57BL/6 mice were i.p. injected with LPS for 6h. The mouse IL22 ELISA kit cross-reacted with mIL22 and humanized IL22.


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