hMUC1

Nomenclature

C57BL/6Smoc-Muc1tm(hMUC1)Smoc

Cat. NO.

NM-HU-220409

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Muc1

Synonyms

EMA; CD227; Muc-1

Chromosome

3

NCBI ID

17829

MGI ID

97231

Ensembl ID

ENSMUSG00000042784

Pubmed

Muc1

Human Ortholog

MUC1

Model Description

The endogenous mouse Muc1 gene was replaced by human MUC1 gene.

Validation Data

image.png

Fig.1 Detection of MUC1 expression in stomach by RT-PCR. 

Wild type: only one band at 375 bp with primers F1/R1(mMuc1);

Homozygous: only one band at 267 bp with primers F2/R2(hMUC1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human MUC1 expression in hMUC1 knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human MUC1 antibody cross-reacted with mouse MUC1 and humanized MUC1. 

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