hIFNAR1

Nomenclature

C57BL/6Smoc-Ifnar1tm(hIFNAR1)Smoc

Cat. NO.

NM-HU-220355

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ifnar1

Synonyms

Ifar; IFN-alpha/betaR; Ifrc

NCBI ID

15975

MGI ID

107658

Ensembl ID

ENSMUSG00000022967

Pubmed

Ifnar1

Human Ortholog

IFNAR1

Model Description

The endogenous mouse Ifnar1 gene was replaced by human IFNAR1 gene.

Validation Data

image.png

Fig.1 Detection of IFNAR1 expression in thymus and subcutaneous fat pad by RT-PCR. 

Wild type: only one band at 262 bp with primers F1/R1(mIfnar1);

Homozygous:  only one band at 471 bp with primers F2/R2(hIFNAR1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human IFNAR1 expression in the male C57BL/6 WT mouse (8-10 weeks old) and hIFNAR1 knockin mice (12 weeks old) by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, Hela cells. (Antibody Cat No.TA377351)

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