dFCGRT

Nomenclature

C57BL/6JSmo-Fcgrttm1(dFCGRT)Smoc

Cat. NO.

NM-HU-241422

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Fcgrt

Model Description

The endogenous mouse Fcgrt gene was replaced by dog FCGRT gene.

Validation Data

image.png

Fig.1 Detection of FCGRT expression in the mammary gland and kidney by RT-PCR. (male in both group)

Wild type: only one band at 357 bp with primers F1/R1(mFcgrt);

Homozygous:  only one band at 343 bp with primers F2/R2(dFCGRT).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of dog FCGRT expression in the male C57BL/6 WT mouse (8-10 weeks old) and dFCGRT knockin mice (10 weeks old) by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, humanized heart.


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