Sox10-2A-Cre

Nomenclature

C57BL/6Smoc-Sox10em(2A-Cre)Smoc

Cat. NO.

NM-KI-220066

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Sox10

Synonyms

gt; Dom; Sox21

NCBI ID

20665

MGI ID

98358

Ensembl ID

ENSMUSG00000033006

Pubmed

Sox10

Human Ortholog

SOX10

Model Description

2A-Cre expression cassette was knocked into the Sox10 gene stop codon site. The target gene is associated with pigment, and heterozygotes are recommended for mating in breeding.

Validation Data

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Fig 1. Photographs of the back and abdomen of Sox10Cre/+; Rosa26tdTomato/+ mice.

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Fig 2. Cre-mediated recombination in occipital skull of Sox10Cre/+; Rosa26tdTomato/+ mice.

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Fig 3. Cre-mediated recombination in intestines of Sox10Cre/+; Rosa26tdTomato/+ mice.

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Fig 4. Detection of tdTomato(red) in various tissues of Sox10Cre/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, pituitary gland, eyeball, heart, lung, liver, stomach, salivary gland, kidney, pancreas, small intestine, colon, testis, epididymis, thymus and tongue. A few cells expressed in brown fat, adrenal gland, spleen, muscle, skin. (8-week old, male) (For more detailed information please contact our technical advisor.) 


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