SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Tg(hIL-8)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225012
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Strain Name：C57BL/6JSmo-Il10tm4(hIL10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000063
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6JSmo-Il11tm1(hIL11)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204981
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Strain Name：C57BL/6JSmo-Il11tm1(hIL11)Il11ra1tm1(hIL11RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210372
Research Application：inmmue therapy;drug screening
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Strain Name：C57BL/6JSmo-Il12atm3(hIL12A)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000056
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6JSmo-Il12betm3(hIL12B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000057
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6JSmo-Il23atm3(hIL23A)Il12btm3(hIL12B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-233778
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Strain Name：C57BL/6JSmo-Il13tm2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190069
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cJSmo-Il13tm2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220019
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Strain Name：C57BL/6JSmo-Il13tm2(hIL13)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220024
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