hCD19/hCD3EDG(BALB/c)

Nomenclature

BALB/cAnSmoc-Cd19em(hCD19)Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc

Cat. NO.

NM-XA-240066

Strain State

Embryo cryopreservation

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Model Description

The hCD3EDG(BALB/c)(NM-HU-220122) was crossed with hCD19(BALB/c)(NM-HU-220606) to generate hCD19(BALB/c)/hCD3EDG(BALB/c) mice.

Validation Data

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Fig.1 Detection of immune phenotype in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.(male, n=3)

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Fig.2 Detection of phenotype in Peripheral blood in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.3 Detection of phenotype in Spleen in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.4 Detection of phenotype in Lymph node in WT BALB/c and HO/HO hCD3EDG/hCD19 mice.

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Fig.5 Blinatumomab injections were repeated daily for 5 days and immune cells in the PB of mice after therapy were measured by flow cytometry(n=6). Average ± SEM;*P<0.05,**P<0.01,***P<0.001;(Student' s t test)

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