Myf6-CreERT2

Nomenclature

C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc

Cat. NO.

NM-KI-200125

Strain State

Repository Live

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Gene Summary

Gene Symbol
Myf6

Synonyms

MRF4; bHLHc4; herculin

NCBI ID

17878

MGI ID

97253

Ensembl ID

ENSMUSG00000035923

Pubmed

Myf6

Human Ortholog

MYF6

Model Description

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.
Research Application：Cre recombinase tool

Validation Data

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Fig.1 CreERT2 mediated recombination in muscle of Myf6 CreERT2/+;Rosa26 tdTomato/+ mice.

Publications

α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure
References：Cell Research

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