Acta2-CreERT2

Fig. 1 CreERT2-mediated recombination in the pancreas of Acta2^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the vascular smooth muscle cells of Acta2 ^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected prior to tamoxifen exposure. 

Fig. 2 Detection of tdTomato(red) in various tissues of Acta2^CreERT2/+; Rosa26^tdTomato/+ mice. CreERT2 mediated recombination can be detected in the pancreas, kidney, brain, heart, lung, liver, thymus, submandibular gland, brown fat, ovary, muscle, thymus, spleen, large intestine and small intestine. Leakiness were detected in the above tissues prior to tamoxifen exposure. Tdtomato expression can not be observed in the pituitary gland. (For more detailed information please contact our technical advisor.)