Fcgrt-KO

Nomenclature

C57BL/6JSmo-Fcgrtem1Smoc

Cat. NO.

NM-KO-00133

Strain State

Repository Live

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Gene Summary

Gene Symbol
Fcgrt

Synonyms

FcRn

NCBI ID

14132

MGI ID

103017

Ensembl ID

ENSMUSG00000003420

Pubmed

Fcgrt

Human Ortholog

FCGRT

Model Description

Fcgrt-KO mice (Stock No.NM-KO-00133）carry a knockout allele derived from the targeted deletion of exon 1-4.
Research Application：Immunotherapy,drug screening

Validation Data

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Fig.1 Detection of Fcgrt expression in Fcgrt-KO by RT-PCR. 

Wild type and Homozygous: one band at 650 bp with primers F1/R1(mFcgrt) and one band at 123 bp with primers F/R(mGapdh). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of mouse IgG expression in serum by ELISA. 

Abbr. HO, homozygous; WT, wild type.

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Fig.3 Detection of ALB expression in serum by Blood Biochemistry. 

Abbr. HO, homozygous; WT, wild type.


Publications 1piece

1. Liver macrophages and sinusoidal endothelial cells execute vaccine-elicited capture of invasive bacteria
Published year：2023 References：Sci Transl Med

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