Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6JSmo-Gbaem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-205010
Disease Connection:Gaucher's disease, Gaucher's disease type I, Gaucher's disease type II
mouse
Strain Name:C57BL/6JSmo-Gba2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-250524
mouse
Strain Name:C57BL/6JSmo-Gbe1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201282
Disease Connection:glycogen storage disease IV
mouse
Strain Name:C57BL/6Smoc-Gbf1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6Smoc-Gbgt1em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Gbp10em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2100380
mouse
Strain Name:C57BL/6Smoc-Gbp11em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Gbp2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201589
mouse
Strain Name:C57BL/6JSmo-Gbp2bem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201590
mouse
Strain Name:C57BL/6JSmo-Gbp4em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2107932
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