Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

mouse
Strain Name:C57BL/6JSmo-Fgd4em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200960
Disease Connection:Charcot-Marie-Tooth disease type 4H
mouse
Strain Name:C57BL/6Smoc-Fgd6em1Smoc
Strain State:Developing | Cat. NO.:TBD
mouse
Strain Name:C57BL/6JSmo-Fgf1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200200
Research Application:Therapeutic antibody target
mouse
Strain Name:C57BL/6JSmo-Fgf1em3Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-240227
mouse
Strain Name:C57BL/6JSmo-Fgf11em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-2106183
mouse
Strain Name:C57BL/6JSmo-Fgf12em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190958
Research Application:Fibroblast growth factor, VSMC lineage differentiation
mouse
Strain Name:C57BL/6JSmo-Fgf13em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210337
mouse
Strain Name:C57BL/6JSmo-Fgf14em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200961
Disease Connection:spinocerebellar ataxia type 27
mouse
Strain Name:C57BL/6JSmo-Fgf17em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-250583
mouse
Strain Name:C57BL/6JSmo-Fgf2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200201
Research Application:Therapeutic antibody target
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