Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Dkkl1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Dlatem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dldem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-240409
Mice
Strain Name:C57BL/6Smoc-Dlec1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dleu2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201145
Mice
Strain Name:C57BL/6JSmo-Dlg1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226254
Mice
Strain Name:C57BL/6Smoc-Dlg2em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Dlg3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2113886
Disease Connection:non-syndromic X-linked intellectual disability
Mice
Strain Name:C57BL/6JSmo-Dlg3em2Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226157
Mice
Strain Name:C57BL/6JSmo-Dlg4em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190951
Disease Connection:Williams-Beuren syndrome
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