Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6JSmo-Ddb2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-2103971
Disease Connection:xeroderma pigmentosum group E
Mice
Strain Name:C57BL/6JSmo-Ddcem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-231425
Mice
Strain Name:C57BL/6Smoc-Ddhd1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Ddhd2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200944
Disease Connection:hereditary spastic paraplegia 54
Mice
Strain Name:C57BL/6Smoc-Ddi1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Ddi2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-2103122
Mice
Strain Name:C57BL/6Smoc-Ddiasem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Ddit3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-205039
Mice
Strain Name:C57BL/6JSmo-Ddit4em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-191072
Research Application:Vision, retina; disc degeneration (IDD); cancer
Mice
Strain Name:C57BL/6JSmo-Ddit4em2Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-226116
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