Models

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Col5a1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201257
Disease Connection:Ehlers-Danlos syndrome classic type 1
Mice
Strain Name:C57BL/6Smoc-Col5a3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200137
Research Application:Therapeutic antibody target
Mice
Strain Name:C57BL/6Smoc-Col6a1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200138
Disease Connection:Bethlem myopathy
Mice
Strain Name:C57BL/6Smoc-Col6A2em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Col6a3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200827
Mice
Strain Name:C57BL/6Smoc-Col6A4em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Col6a5em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-205640
Research Application:secreted protein
Mice
Strain Name:C57BL/6Smoc-Col6a6em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-205624
Research Application:secreted protein
Mice
Strain Name:C57BL/6Smoc-Col8a1em1/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-230423
Mice
Strain Name:C57BL/6Smoc-Col8A2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-2100074
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