Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Chd7em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2111901
Disease Connection：CHARGE syndrome
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Strain Name：C57BL/6Smoc-Chd8em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201140
Disease Connection：autism spectrum disorder
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Strain Name：C57BL/6Smoc-Chek1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190561
Research Application：cancer research
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Strain Name：C57BL/6Smoc-Chek2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-2107927
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Strain Name：C57BL/6Smoc-Chgbem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190935
Research Application：Adrenal chromaffin cell function, catecholamine secretion, Parkinson's disease
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Strain Name：C57BL/6Smoc-Chia1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190776
Research Application：The variations in this gene can lead to asthma susceptibility.
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