Vip-IRES-Cre

Nomenclature

C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc

Cat. NO.

NM-KI-200100

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Vip

Model Description

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.
Research Application:Cre recombinase tool

Validation Data

image.png

Fig. 1 Cre-mediated recombination in the brain of VipCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex of VipCre/+; Rosa26tdTomato/+ mouse. 

vip.png

Fig. 2 Detection of tdTomato(red) in various tissues of VipCre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the cortex, olfactory bulb, colon, epididymis, kidney, muscle, spleen, stomach, thymus, brown fat, intestine, heart, retina, liver, lung, pancreas, testis, salivary gland and skin. (For more detailed information please contact our technical advisor.)



You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more