Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Ephb1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240717
Mice
Strain Name:C57BL/6Smoc-Ephb2em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-231275
Mice
Strain Name:C57BL/6Smoc-Ephb3em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-240718
Mice
Strain Name:C57BL/6Smoc-Ephb4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231231
Mice
Strain Name:C57BL/6Smoc-Ephb6em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-253956
Mice
Strain Name:C57BL/6Smoc-Ephx1em1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-210007
Mice
Strain Name:C57BL/6Smoc-Ephx2em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2102796
Mice
Strain Name:C57BL/6Smoc-Ephx3em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Ephx4em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Epm2aem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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