Models

Conditional Knockouts

In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.

Mice
Strain Name:C57BL/6Smoc-Slc51bem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Slc52a2em2(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231344
Mice
Strain Name:C57BL/6JSmo-Slc52a3tm1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2101131
Mice
Strain Name:C57BL/6JSmo-Slc5a1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2101495
Mice
Strain Name:C57BL/6Smoc-Slc5a10em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Slc5a11em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6JSmo-Slc5a12em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2116493
Mice
Strain Name:C57BL/6JSmo-Slc5a2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-226211
Mice
Strain Name:C57BL/6Smoc-Slc5a3em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Slc5a4aem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
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