In the conditional knockout mouse model, the gene of interest is deleted only in selected cells, as determined by a tissue-specific promoter. Conditional knockout mice are usually generated using Cre-LoxP, Dre-Rox, or Flp-Frt recombination systems for permanent gene alterations in specific tissues. The targeted fragment to be knocked out is flanked by LoxP elements. Floxed mice are then bred with tissue-specific Cre or CreERT2 mice, and sequences between LoxP sites will be removed from the offspring’s genome in a spatial and/or temporal manner.
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Strain Name：C57BL/6JSmo-Ptgfrem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-241394
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Strain Name：C57BL/6JSmo-Ptgirem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200272
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Strain Name：C57BL/6JSmo-Ptgr1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253458
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Strain Name：C57BL/6JSmo-Ptgs1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200128
Research Application：Studies on arachidonic acid metabolism and cytochrome P450
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Strain Name：C57BL/6JSmo-Ptgs2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200129
Research Application：Correlation Study of Oxytocin Signal Transduction Pathway and Immune Response FcεRI Pathway
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