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U-GEMMs

About 42,431 results
Mice

Nr5a1-Flox

Strain Name:C57BL/6Smoc-Nr5a1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200071

These mice carry loxP sites flanking exon 4 of Nr5a1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nr5a1 gene.

Mice

Ucp1-Cre

Strain Name:C57BL/6Smoc-Ucp1em2(Kozak-Cre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190105

A Kozak-Cre-WPRE-pA expression cassette was knocked into the Ucp1 gene start codon site.

Mice

Atp4b-2A-CreERT2

Strain Name:C57BL/6Smoc-Atp4bem1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200240

A 2A-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene stop codon site.

Mice

Tigre-TetO-hEGFR*del19-IRES-GFP-2A-Cre

Strain Name:C57BL/6Smoc-Igs7em1(tetO-EGFR-del19-IRES-GFP-2A-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200258

A tetO-EGFR-del19-IRES-GFP-2A-Cre expression cassette was knocked into the TIGRE locus.

Mice

R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190074

These mice harbor a CAG-LSL-IDH1(R132H)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190009

A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein.

Mice

Foxn1-IRES-Cre

Strain Name:C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Il4-IRES-tdTomato

Strain Name:C57BL/6Smoc-Il4em3(IRES-tdTomato-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200028

A IRES-tdTomato-polyA expression cassette was knocked into the Il4 gene stop codon site.

Mice

hIGHG4

Strain Name:C57BL/6Smoc-Ighg1tm1(hIGHG4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225092

The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene.

Mice

hCD3EDG

Strain Name:C57BL/6-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State:Repository Live | Cat. NO.:NM-HU-220120

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

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