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U-GEMMs

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Mice

hHER3

Strain Name：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200234

The endogenous mice Erbb3 gene was replaced by human HER3 gene.

Mice

hHER3(2)

Strain Name：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225068

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

Aatf-Flox

Strain Name：C57BL/6Smoc-Aatfem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234849

These strains carry loxP sites flanking exon 6 of Aatf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aatf gene.

Mice

hIGFBP2

Strain Name：C57BL/6Smoc-Igfbp2tm1(hIGFBP2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225085

The endogenous mouse Igfbp2 gene was replaced by human IGFBP2 gene.

Mice

Btd-KO

Strain Name：C57BL/6Smoc-Btdem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200630

Exon 2-3 of Btd gene was deleted to generate Btd knockout mice.

Mice

Angptl6-KO

Strain Name：C57BL/6Smoc-Angptl6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

hLILRB2-hLILRB3-Tg

Strain Name：C57BL/6Smoc-Tg(loxp-LILRB2-LILRB3-FRT-PGK-PuropolyA-FRT-lox2272)
Strain State：Repository Live | Cat. NO.：NM-TG-220136

These transgenic mice harbor loxp-hLILRB2-hLILRB3-FRT-PGK-PuropolyA-FRT-lox2272 expression cassettes.

Mice

Aldh7A1-KO

Strain Name：C57BL/6Smoc-Aldh7A1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2-5 of Aldh7A1 gene was deleted to generate Aldh7A1 knockout mice.

Mice

hCD3EDG/hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220117

hCD3EDG/hCD40(NM-HU-220116) mice were crossed with hCD3EDG/h4-1BB(2)(NM-HU-220110) to generate hCD3EDG/hCD40/h4-1BB(2) mice.

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