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U-GEMMs

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Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E))Cd38em2(hCD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

Mice

hTLR8/hPD-1

Strain Name：C57BL/6Smoc-Tlr8tm2(TLR8)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200276

hTLR8(NM-HU-190044) was crossed with hPD-1(NM-HU-00015)to generate hTLR8/hPD-1 mice

Mice

hVEGFR2

Strain Name：C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00098

The endogenous mouse Kdr gene was replaced by human KDR gene .

Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9em2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

Akt2-KO

Strain Name：C57BL/6Smoc-Akt2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190742

Exon 3-4 of Akt2 gene was deleted to generate Akt2 knockout mice.

Mice

hCD40/hCD40L

Strain Name：C57BL/6Smoc-CD40em2(hCD40)Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200268

hCD40（NM-HU-00076）was crossed with hCD40L（NM-HU-2000033）to generate hCD40/hCD40L mice

Mice

hNECTIN4

Strain Name：C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210016

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Il12a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

Ly6g-2A-CreERT2

Strain Name：C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene start codon site.

Mice

Cd8a-2A-tdTomato-2A-Luc

Strain Name：C57BL/6Smoc-Cd8aem(T2A-tdTomato-P2A-Luciferase)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225025

T2A-tdTomato-P2A-Luciferase expression cassette was knocked into the Cd8a gene .

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