U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190076
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18052
Research Application:Tumor research; drug screening
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hMSLN-IRES-Luciferase-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225094
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-HA-hMYCN-IRES-BFP-Wpre-polyA)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225000
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NFE2L2(G81S)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190077
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18050
Research Application:Tumor research; drug screening
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190065
Disease Connection:breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hPLAG1-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215002
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200051
Research Application:Cancer and aging research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-REST4-IRES-EGFP-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200052
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