U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Tpbgem1(hTPBG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200239
Mice
Strain Name:C57BL/6Smoc-Trem2tm(hTRem2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220502
Mice
Strain Name:C57BL/6Smoc-Tacstd2em(hTACSTD2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215022
Mice
Strain Name:C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00098
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tg(pAtp4b-hCLDN18.2)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-220197
Mice
Strain Name:C57BL/6Smoc-Tg(pCdh16-hENPP3)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-220195
Mice
Strain Name:C57BL/6Smoc-Tgtn(pWap-ERBB2)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225013
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00081
Research Application:cancer research;Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190069
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190068
Research Application:cancer research
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