SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il6raem1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State：Developing | Cat. NO.：NM-HU-210027
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Lair1tm1(hLILRA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225074
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Strain Name：C57BL/6Smoc-Tg(hLILRB1-hLILRB4)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-220022
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Strain Name：C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210024
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210401
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Strain Name：C57BL/6Smoc-Pdgfratm1(hPDGFRA)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200250
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Strain Name：C57BL/6Smoc-Pdgfrbtm(hPDGFRB)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-230050
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Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190010
Research Application：Immune-related
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Strain Name：BALB/cAnSmoc-Tnfrsf1bem(hTNFRSF1B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220499
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