SMOC has developed a set of mouse models expressing humanized cytokines receptors. These models are suitable to assess the efficacy of drugs targeting cytokines receptors in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il15ratm1(hIL15RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215070
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Strain Name：C57BL/6Smoc-Il17ratm1(hIL17RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190049
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Il17ratm1(hIL17RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220015
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Strain Name：C57BL/6Smoc-Il17rbtm2(hIL17RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200225
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Strain Name：C57BL/6Smoc-Il18r1tm1(hIL18R1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-210029
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-IL18raptm1(hIL18RAP)Smoc
Strain State：Developing | Cat. NO.：NM-HU-210030
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000070
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000067
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il1rl2em1(hIL1RL2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215057
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Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Research Application：inmmue therapy；drug screening
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