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Models

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Mice

Aldh1L2-KO

Strain Name：C57BL/6Smoc-Aldh1L2em1Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

Exon 2 of Aldh1L2 gene was deleted to generate Aldh1L2 knockout mice.

Mice

Pdgfra-CreERT2

Strain Name：C57BL/6Smoc-Pdgfraem(CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225036
Validation Data：Presence

CreERT2 expression cassette was knocked into the Pdgfra gene .

Mice

Erbb2-Flox

Strain Name：C57BL/6Smoc-Erbb2em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220557
Validation Data：Absence

These mice carry loxP sites flanking exon 2 of Erbb2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Erbb2 gene.

Mice

hIL13

Strain Name：C57BL/6Smoc-Il13em2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190069
Validation Data：Presence

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

Ube3a-KO

Strain Name：C57BL/6Smoc-Ube3aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200599
Validation Data：Absence

Exon 5 of Ube3a gene was deleted to generate Ube3a knockout mice.

Mice

Vip-IRES-Cre

Strain Name：C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200100
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

Mice

hDLL4

Strain Name：C57BL/6Smoc-Dll4em1(hDLL4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000020
Validation Data：Presence

The endogenous mouse Dll4 gene was replaced by human DLL4 gene.

Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118
Validation Data：Presence

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

Ifng-Venus-Luc

Strain Name：C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18041
Validation Data：Presence

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130
Validation Data：Presence

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

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