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Mice

Pdcd1-DTR-2A-tdTomato

Strain Name：C57BL/6Smoc-Pdcd1em1(DTR-2A-tdTomato-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200225
Validation Data：Absence

A DTR-2A-tdTomato-WPRE-pA expression cassette was knocked into the Pdcd1 gene start codon site.

Mice

Agxt-KO

Strain Name：C57BL/6Smoc-Agxtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210152
Validation Data：Absence

Exon 3-8 of Agxt gene was deleted to generate Agxt knockout mice.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

Zmpste24-KO

Strain Name：C57BL/6Smoc-Zmpste24em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18011
Validation Data：Absence

Exon4-6 of Zmpste24 gene were deleted to generate Zmpste24 knockout mice.

Mice

R26-CAG-LSL-zsGreen

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-zsGreen)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200045
Validation Data：Presence

These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hCRBN

Strain Name：C57BL/6Smoc-Crbnem1(hCRBN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225071
Validation Data：Presence

The endogenous mouse Crbn gene was replaced by human CRBN gene.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075
Validation Data：Absence

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

Calb2-IRES-Cre

Strain Name：C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200102
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

Krt14-CreERT2

Strain Name：C57BL/6Smoc-Krt14em2(CreERT2-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190024
Validation Data：Presence

A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene.

Mice

Adk-KO

Strain Name：C57BL/6Smoc-Adkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201237
Validation Data：Absence

Exon 4 of Adk gene was deleted to generate Adk knockout mice.

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