Welcome to Advanced Search

Models

About 43,966 results
Mice

a-IRES-Cre

Strain Name：C57BL/6Smoc-atm1(Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200027
Validation Data：Absence

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

hCB1

Strain Name：C57BL/6Smoc-Cnr1em1(hCB1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225027
Validation Data：Presence

The endogenous mouse Cnr1 gene was replaced by human CB1 gene.

Mice

Cd19-IRES-EGFP-Luc

Strain Name：C57BL/6Smoc-Cd19em1(IRES-EGFP-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200058
Validation Data：Absence

A IRES-EGFP-Luci expression cassette was knocked into the Cd19 gene stop codon site.

Mice

Ccr2-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Ccr2em1(IRES-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210102
Validation Data：Presence

IRES-DTRGFP expression cassette was knocked into the Ccr2 gene .

Mice

hSTING

Strain Name：C57BL/6Smoc-Tmem173em2(hTMEM173)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190036
Validation Data：Presence

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000083
Validation Data：Presence

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

Mice

Upk3a-2A-GFPCre

Strain Name：C57BL/6Smoc-Upk3aem1(2A-EGFP-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210003
Validation Data：Absence

2A-EGFP-Cre expression cassette was knocked into the Upk3a gene .

Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056
Validation Data：Absence

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

Itgax-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Itgaxem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204992
Validation Data：Presence

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Itgax gene .

Mice

CAG-LSL-dCas9-SPH-Tg

Strain Name：C57BL/6Smoc-Tg(CAG-LSL-dCas9-SPH)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00025
Validation Data：Absence

Cre-dependent SunTag-p65-HSF1 (SPH) transgenic mice were generated with piggyBac transposon system in F1 zygotes and crossed with wild type C57BL/6 mice., SPH transgenic mouse containing HA-tagged dCas9 fused with 10xGCN4, which is linked with p65-HSF1 and EGFP in tandem via P2A and T2A respectively. The transgene is driven by the ubiquitous CAG promoter and interrupted by a loxP-stop-loxP (LSL) cassette to render Cas9 expression inducible by the Cre recombinase. Expression of dCas9 can be detected using primary antibody: rabbit monoclonal antibody to HA-tag (1:1000, #3724, CST45) and secondary antibody: goat anti-rabbit Alexa Fluor 488 (1:1000, #A-11034, Thermo Fisher). *This strain is a client-donated line. The donor's publication indicates that fluorescence was observed by immunofluorescence. The JAX description of this strain also explicitly states that fluorescence cannot be directly observed.

Email Back to top