hB7H3

Nomenclature

C57BL/6Smoc-Cd276tm2(hB7H3)Smoc

Cat. NO.

NM-HU-00107

Strain State

Repository Live

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Gene Summary

Gene Symbol
CD276

Synonyms

B7H3;B7-h3; B7RP-2; AU016588; 6030411F23Rik

NCBI ID

102657

MGI ID

2183926

Ensembl ID

ENSMUSG00000035914

Pubmed

CD276

Human Ortholog

CD276

Model Description

在将小鼠CD276基因的exon 2-3替换为人源CD276基因 exon2-3对应序列，从而表达人CD276嵌合蛋白。
Research Application：肿瘤研究；免疫治疗；药物筛选

Validation Data

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图1. 流式检测外周血巨噬细胞和DC细胞中hB7H3的表达情况

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图2. 流式检测脾脏巨噬细胞和DC细胞中hB7H3的表达情况

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图3. 流式检测骨髓巨噬细胞和DC细胞中hB7H3的表达情况

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图4. 流式检测肝来源的内皮细胞(CD11b- CD31+)中hB7H3的表达情况

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图5. 流式检测肺来源的内皮细胞(CD45- CD31+)中hB7H3的表达情况

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图6. 流式检测睾丸来源的内皮细胞(CD45- CD31+)中hB7H3的表达情况

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