R26-CAG-LSL-mCherry-EGFP-LC3
Nomenclature
C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-mCherry-EGFP-Map1lc3a-pA)Smoc
Cat. NO.
NM-KI-00124
Strain State
Repository Live
Gene Summary
Gene Symbol
Gt(ROSA)26Sor
Model Description
Validation Data
Fig1. Detection of EGFP and RFP fluorescence intensity in brain, heart and liver tissues of R26-CAG-mCherry-EGFP-LC3 mice. Starvation(+): The mice were fasted for 48 hours; Starvation(-): The mice were fed normally.
Fig2. Detection of EGFP and RFP puncta in liver tissue sections of R26-CAG-mCherry-EGFP-LC3 mice. Starvation for 48 h increased the ratio of RFP/EGFP fluorescence expression in liver tissue of R26-CAG-mCherry-EGFP-LC3 mice. These results suggested there was increased fusion of autophagosomes with lysosomes after 48h starvation. Starvation(+): The mice were fasted for 48 hours; Starvation(-): The mice were fed normally.
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