Syn1-IRES-CreERT2

Nomenclature

C57BL/6Smoc-Syn1em1(IRES-CreERT2)Smoc

Cat. NO.

NM-KI-231789

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Syn1

Model Description

The IRES-CreERT2 expression cassette was knocked into the Syn1 gene stop codon site.

Validation Data

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Fig 1. Cre-mediated recombination in brain of Syn1CreERT2/+; Rosa26tdTomato/+ mice.

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Fig 2. Cre-mediated recombination in brain of Syn1CreERT2/+; Rosa26tdTomato/+ mice.

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Fig 3. Detection of tdTomato (red) in various tissues of Syn1CreERT2/+; Rosa26tdTomato/+ mice. Expression tissues include: brain, retina, islet, pituitary. A few cells expressed in spinal cord, heart, lung, liver, adrenal gland, kidney, small intestine, colon, muscle and thymus. Tissues that unexpressed include  stomach, salivary glands, brown fat, spleen, uterus, skin. Tamoxifen induction began at 35 days of age, with testing at 45 days. (45-day old, female) (For more detailed information please contact our technical advisor.) 


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