Animal Welfare
Shanghai Model Organisms Co., Ltd. Institutional Animal Care and Use Committee (hereinafter referred to as "Shanghai Model Organisms IACUC") adheres strictly to the following normative documents:
Guide for the Care and Use of Laboratory Animals, 8th Edition
Institution Animal Care and Use Committee Guidebook 2002 2th Edition
GB/T 27416-2014 Laboratory Animal Institutions - General Requirements for Quality and Competence
CNAS-CL60 Accreditation Criteria for Quality and Competency of Laboratory Animal Care and Use Institutions
Shanghai Municipal Laboratory Animal Management Regulations 1997
Responsible for the supervision and assessment of all animal care and use plans, as well as their contents, within the company. All animal-related activities in SMOC, including animal and laboratory facilities, adhere strictly to the IACUC regulations.
The main functions of SMOC IACUC are as follows:
Review and approve all applications for and changes to animal experiments, and provide the IACUC number that complies with animal ethics after such approval.
Conduct regular inspections on the animal facilities of the institution.
Review all projects related to animal care and use.
Monitor and prevent the diseases of animals in the facilities of the institution.
Perform qualification review and training for the personnel who are responsible for the handling of laboratory animals.
Supervise the selection and use of anaesthetics and analgesics.
Provide support for pre-operative preparation and post-operative care of laboratory animals.
Check if the implementation of euthanasia of laboratory animals is in accordance with international standards.
SMOC IACUC has the right to suspend any non-compliant activities involving animals.
By adhering strictly to the SMOC IACUC regulations, we guarantee the consistent high-level product and service quality. If you have any inquiries or suggestions, please feel free to contact us by phone or email!
Popular articles
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
Learn more你一定听说过Cre-lox重组系统,无论你是否直接进行过基因操作。由于Cre-lox系统具有操作简单、重组率高的优点,如今已经成为体内外遗传操作的强有力工具。利用Cre-lox系统,可以在特定细胞、组织或整个生物体,甚至在特定时间点敲除或表达某个基因,实现对特定基因的时空特异性操作,这对基因功能的研究和人类疾病动物模型的建立都具有深刻影响。
Learn more