Lat-Y136F
Nomenclature
C57BL/6Smoc-Latem1(Y136F）Smoc
Cat. NO.
NM-KI-200249
Strain State
Repository Live
Gene Summary
Gene Symbol
Lat
Model Description
These mice carry a p.Y136F mutation of Lat gene.
Disease Connection
Validation Data
Fig1. Spleen (left) and mesenteric lymph nodes (right) from 8-week-old wild-type and Lat-Y136F mice.
Fig2. Immunotype in Lat-Y136F mice in lymph nodes.
Fig3. Immunotype in Lat-Y136F mice in peripheral blood.
Fig4. Immunotype in Lat-Y136F mice in spleen.
Fig5. Immunotype in Lat-Y136F mice in thymus.
Fig6. Analysis of mIgE expression in the serum by ELISA in WT C57BL/6 and HO Lat-Y136F mice (female, 8-9wks, n=5).
The expression of mIgE in the serum increased significantly in the homozygous KI mouse.
Fig7. Analysis of mIgG1 expression in the serum by ELISA in WT C57BL/6 and HO Lat-Y136F mice (female, 8-9wks, n=5).
The expression of mIgG1 in the serum increased significantly in the homozygous KI mouse.
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