hIGHG1

Nomenclature

C57BL/6Smoc-Ighg1tm1(hIGHG1)Smoc

Cat. NO.

NM-HU-225091

Strain State

Repository Live

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Gene Summary

Gene Symbol
Ighg1

Model Description

The endogenous mouse Ighg1 gene was replaced by human IGHG1 gene.


Validation Data

image.png

Fig.1 Detection of IGHG1 expression in lung by RT-PCR (8-9wks, male). 

Wild type: only one band at 298 bp with primers F1/R1 (mIghg2c);

Homozygous: only one band at 377 bp with primers F2/R2 (hIGHG1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hIGHG1 expression in serum by ELISA (HO: 6wks, WT: 8-12wks, male, n=3).

Abbr. HO, homozygous; WT, wild type.


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