hGCGR
Nomenclature
C57BL/6Smoc-Gcgrem(hGCGR)Smoc
Cat. NO.
NM-HU-215004
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Cxcr5
Model Description
The endogenous mice Gcgr gene was replaced by human GCGR gene.
Validation Data
Fig1. Detection of GCGR expression in liver by RT-PCR.
Wild type: only one band at 589 bp with primers F1/R1(mGcgr);
Homozygous: only one band at 501 bp with primers F2/R2(hGCGR).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of hGCGR expression in hGCGR Mice by WB.
Abbr. M,marker; HO, homozygous; WT, wild type.
Note. The anti-human GCGR Antibody cross-reacted with mouse GCGR and humanized GCGR.
Fig3. Detection of hGCGR expression in Kidney in hGCGR KI mice
Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.
Fig4. Detection of hGCGR expression in Liver in hGCGR KI mice.
Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
