U-GEMMs

Metabolic Targets

SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.

Mice
Strain Name:NOD-PrkdcscidIl2rgem1Fcgrtem1(B2m-FCGRT)Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-018
Research Application:Antibody drug metabolism; drug screening
Mice
Strain Name:C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200221
Disease Connection:familial Mediterranean fever
Mice
Strain Name:C57BL/6Smoc-Tg(pAlb-hAPOB)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-225002
Mice
Strain Name:C57BL/6Smoc-Tgtn(pAlb-hAPOB-WPRE-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-234136
Mice
Strain Name:C57BL/6Smoc-Tgtn(pAlb-hAPOB-3’UTR-pA-pAlb-hLPA-3’UTR-pA)1Smoc(V2)
Strain State:Repository Live | Cat. NO.:NM-TG-231783
Mice
Strain Name:C57BL/6Smoc-Tg(pAlb-hAPOB-WPRE-pA-pAlb-hLPA-WPRE-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-232197
Mice
Strain Name:C57BL/6Smoc-Tg(pAlb-hLPA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225001
Mice
Strain Name:C57BL/6Smoc-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-231782
Mice
Strain Name:C57BL/6Smoc-Tg(pAlb-hLPA-WPRE-pA)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-232196
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215053
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