hALB/hFCRN

Nomenclature

C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc

Cat. NO.

NM-HU-200278

Strain State

Repository Live

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Gene Summary

Gene Symbol
FCGRT

Gene Symbol
ALB

Gene Symbol
Fcgrt

Model Description

hALB(NM-HU-200003)was crossed with hFcRn(NM-HU-190070)to generate hALB/hFCRN mice

Validation Data

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Fig1. Detection of hALB and mALB expression in plasma by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

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Fig2. Expression at mRNA level by RT-PCR in hALB&hFCRN dKI Mice.

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig3. Expression characterization of hFCRN in hALB/hFCRN dKI mice by Western blot. 

Abbr. HO, homozygous; WT, wild type.

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Fig4. In vivo PK profiles of TAA scfv-anti HSA VHH in hALB/hFCRN mice (In cooperation with the third party).

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Fig.5 Blood concentration curves of test articles in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party) 

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Table.1 Noncompartmental Analysis (NCA) results of test articles in hFcRn/hALB dKI mice. (In cooperation with the third party) 

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Fig.7 Fitting curves of blood concentration in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party) 



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